Isabella I 22 April 1451 – 26 November 1504) reigned as Queen of Castile from 1474 until her death. Known for completing the Reconquista, ordering conversion or exile of their Muslim and Jewish subjects, and for supporting and financing Christopher Columbus's 1492 voyage that led to the opening of the New World and to the establishment of Spain as the first global power which dominated Europe and much of the world for more than a century. Isabella, granted the title "the Catholic" by Pope Alexander VI.
